Laser Raman scattering of neurotoxins isolated from the venoms of sea snakes Lapemis hardwickii and Enhydrina schistosa.

Neurotoxins from the venoms of the sea snakes Hydrophis ornatus and Hydrophis lapemoides.

The main neurotoxic components, toxins Hydrophis ornatus a and Hydrophis lapemoides a, were isolated from the venoms of the sea snakes Hydrophis ornatus and Hydrophis lapemoides respectively. The amino acid sequence of toxin Hydrophis ornatus a was deduced to be identical with that of toxin Astrotia stokesii a [Maeda & Tamiya (1978) Biochem. J. 175, 507-517] on the basis of identity of the tryp...

Purification and chemical studies of a toxin from the venom of Lapemis hardwickii (Hardwick's sea snake).

The toxin was isolated from the venom of sea snake, Lapemis hardwickii (Hardwick’s sea snake), through a fourstep purification by column chromatography. The toxin was proven homogenous by zonal electrophoresis, analytical ultracentrifugation, and isoelectric focusing. The toxin was also isolated in crystal form. The lethality of the purified toxin increased 23-fold when compared to the original...

Antivenom Cross-Neutralization of the Venoms of Hydrophis schistosus and Hydrophis curtus, Two Common Sea Snakes in Malaysian Waters

Sea snake envenomation is a serious occupational hazard in tropical waters. In Malaysia, the beaked sea snake (Hydrophis schistosus, formerly known as Enhydrina schistosa) and the spine-bellied sea snake (Hydrophis curtus, formerly known as Lapemis curtus or Lapemis hardwickii) are two commonly encountered species. Australian CSL sea snake antivenom is the definitive treatment for sea snake env...

Variation in yield and lethality of venoms from Iranian snakes

Isolation and characterization of the toxic component of Enhydrina schistosa (common sea snake) venom.

The toxic component from the venom of the common sea snake (Enhydrina schisfosa) was isolated by passage of the venom through a carboxymethyl cellulose column. The preparation, which was shown to be homogeneous by zonal electrophoresis, ultracentrifugation, isoelectric focusing, and gel filtration, had amedian lethal dose 50 % (LD& toward mice of 0.044 pg per g of body weight. The molecular wei...